January 25, 2021

The Niche

Trusted stem cell blog & resources

Carl Zimmer

2 min read

In this post I list some recent interesting stem cell and science pubs including artificial human embryo research. Engineered human embryo research continues. Scientists for years have been advancing the types of embryo-like structures made from both human and other creature’s cells. In a new Nature Cell Bio pub entitled, “A 3D model of a human epiblast reveals BMP4-driven symmetry breaking”, a team led by Eric Siggia pushed this further. See an image from the paper I’ve included that shows signs of the primitive …Read More

3 min read

“If I’m going to the trouble of cloning myself, I want the clone to be a copy of me!” I’m imagining what someone might say if they were told that their expensive and ethically dubious personal cloning efforts produced a clone that was somebody else instead of them. Even if the clone was very similar to the clonee, perhaps like a sibling who was nearly but not quite an identical twin, the clonee might be totally PO’d. When I think about “human “cloning” I …Read More

3 min read

The Future of Genomic Medicine conference last week down in La Jolla at Scripps was one of my favorite meetings ever. I wish I had time to have live blogged it more beyond the one post I did about some gene editing talks. Below I discuss 10 top takeaways from this great meeting that I’m planning to attend regularly in the future. You should go too!

2 min read

Any takers on the idea that we can get radical life extension through new technologies like stem cells, organ replacement, cybernetics, or genetic modification? Or just through healthier living in general? A new Nature paper says there’s a natural limit on human lifespan around age 115 and getting past that is just not going to happen. They don’t discuss (that I saw on a brief look) how new technologies could break this “rule”. Carl Zimmer has a nice NYT article on this development and …Read More

2 min read

I try to catch up on my science reading over the weekends and evenings. Here’s my recommended weekend reading on stem cells & science. Did I miss anything especially cool? Let me know in the comments. Direct reprogramming of skin cells into insulin-producing cells. I love direct reprogramming. Healios and Athersys Enter Into Regenerative Medicine Partnership. Can they together create regen med success? National honor for helping “the blind see” comes from CIRM blog. Fun piece on CRISPR language by Ben Zimmer. ‘Crispr’ Breaks Out Of the Lab. …Read More

2 min read

A lot has been going on in the CRISPR world. Here are some key CRISPR updates. Editas has filed the paperwork on the road to going public as a company. Such an IPO, should it come to fruition, could raise billions of dollars. Will the other CRISPR companies like Caribou and CRISPR Therapeutics follow suit? Simplistically, it seems like the first CRISPR IPO could get the lion’s share of investor money, but then there’s the patent thing hanging over all of this (see below) Patent …Read More

1 min read

Some TGIF stuff to read, think about, and do. Still a few days left to nominate your favorite candidate for my Stem Cell Person of the Year Award for 2015. Who had the most impact this year? Thought outside the box? Let me know. Lots of great nominees already. If you haven’t already, check out the journal Stem Cells’ relatively new webpage, Stem Cell Buzz! If you live in the Bay Area, go to the great upcoming student-run conference at Berkeley on stem cells, …Read More

1 min read

Here’s some thought-provoking weekend reading. ALEXEY. CLINICAL CELL PROCESSING NEWS – PART 1, 2015 BIOPOLITICAL TIMES. MITOCHONDRIAL MISSION CREEP AND THE CLONING CONNECTION CALIFORNIA STEM CELL REPORT. CALIFORNIA’S BOB KLEIN PROPOSES $100 BILLION, INTERNATIONAL STEM CELL/GENOMICS VENTURE CARL ZIMMER. A NEW THEORY ON HOW NEANDERTHAL DNA SPREAD IN ASIA DN LEE. YOU SHOULD KNOW: MICHELLE HUNTER AND EXPLORING NEUROSCIENCE THROUGH ART DRUGMONKEY BLOG. NIH CLUMSILY TRIES TO .. [SOMETHING] … FOR GRANT REVIEWERS ED YONG. FAST-EVOLVING HUMAN DNA LEADS TO BIGGER-BRAINED MICE GORSKI. BLOWING THE ANTIVACCINE DOG WHISTLE AGAIN KELLY HILLS. PRIMUM NON …Read More