January 27, 2021

The Niche

Trusted stem cell blog & resources

Cell Stem Cell

2 min read

It’s usually a tossup as to whether my weekly reads skew more towards stem cells/regenerative medicine or cancer. Other times they are more enriched for genomics and epigenetics articles. Seeds of cancer in normal skin, Nature News & Views Engineering synthetic morphogen systems that can program multicellular patterning, Science. Pig fat can be used to grow jawbones for humans, Science Mag news piece. Pig fat stem cells can aid in jawbone growth. Here’s the original Science Translational Medicine research pub. Inherited myeloproliferative neoplasm risk …Read More

3 min read

What are you reading these days and does it include topics like cell therapies for COVID-19, ALS, regenerative potential of fibroblasts, and why Zoom meetings are so tiring for the brain? I cover those topics and more below with recommended reads including papers and media items. Here’s last week’s recommended reads. Here’s to fibroblasts, which have regenerative activities Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing. This work from a team led by Jeff Biernaskie was published in Cell Stem …Read More

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What are the Best Stem Cell Journals in 2021 and is there a stem cell journal list out there? I’ve covered this topic for many years. In this post I have updated the material from over the years and dug more deeply into the question. Looking for a stem cell journal? A regenerative medicine journal more focused on translation and clinical applications? Something more molecular or cellular? Developmental? Where to go for unbiased info? What about stem cell journal impact factors? Some folks are …Read More

3 min read

I find following both stem cell news and the stream of interesting publications to be kind of fun and thought-provoking. This past week or two has been very busy. Here is a news summary and list of notable pubs. Stem Cell News on Parkinson’s Disease There were a number of interesting developments on the Parkinson’s Disease front. Over at STAT News, Sharon Begley wrote about a “secret” experiment in this piece: A secret experiment revealed: In a medical first, doctors treat Parkinson’s with a …Read More

2 min read

There’s never enough time to get all of one’s science reading done, but we can try! It helps to have a list of “to-read” articles, whether actual research articles or media pieces. In the old days, I remember my mentors saying they literally had “piles” of journal articles on their coffee tables, bathrooms, bedrooms, etc. that they needed to read. Here are some past recommended reads. What would be the digital piles of science articles to try to dig into this week? Here are …Read More

4 min read

What’s on your weekend reads list including stem cell papers? In addition to hard-core research papers, I find some bigger picture publications to be helpful too. Then there are just fun items. Every so often I do a post about things that I’m hoping to find time to read over the weekend or that I’ve recently read. Today’s post is one of those items and here are some interesting science reads related in particular to stem cells, cancer, and CRISPR. Stem cell research and …Read More

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Here in the U.S. we just had our big Thanksgiving holiday, but science goes, stem cells keep growing and needing attention, and it’s another weekend chance to catch up on our paper reading. Here’s this weekend edition of recommended reads including news items and pubs. From Cell Stem Cell: Single-Cell Transcriptome Analysis of Uniparental Embryos Reveals Parent-of-Origin Effects on Human Preimplantation Development. and another there on stem cell machinery in cancer: Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy. …Read More

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The exciting and sometimes downright crazy giant stem cell ecosystem of legit research and unproven stem cell clinics could use a dose of good news now and then. In today post, I highlight some upbeat news and some interesting recent pubs. Enjoy! From a team led by Hina Chaudhry, MD, Director of Cardiovascular Regenerative Medicine at the Icahn School of Medicine at Mt. Sinai, a new PNAS pub, “Multipotent fetal-derived Cdx2 cells from placenta regenerate the heart.” Congrats to first author Sangeetha Vadakke-MadathilThis is a …Read More

2 min read

What are your weekend reads? Many of us scientists read up on specific articles over the weekend that caught our eye during the last week or two. Here are some of my weekend reads plus some other stuff that just generally looked really interesting or unusual. The list includes both primary papers and news articles as well as including biotech news. Enjoy! TGIF. On some of them I at times include positive (or even sometimes snarky comments). Some of the pieces in the science …Read More

3 min read

There’s a new paper in Cell Stem Cell on esophageal organoids that has really caught people’s attention. It is entitled, “3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling.” It comes from a team led by Jianwen Que. Update: I didn’t realize when I first did this post that there were 2 related esophageal organoids papers in the same issue of the journal and the second one led by James M. Wells at Cincinnati Children’s has some cool …Read More