September 21, 2020

The Niche

Knoepfler lab stem cell blog

celularity

6 min read

The FDA and its CBER branch have been doing a good job overall in the last 3+ years to tackle the unproven stem cell clinic problem, but lately on the stem cells for COVID-19 front there is reason for real concern. I believe the agency is taking on major risk overall by clearing a vast number of cell therapy trials for COVID-19 mostly without much data, but the clearance of a few programs by for-profit stem cell clinics is especially problematic in my view. FDA on …Read More

3 min read

What are you reading these days and does it include topics like cell therapies for COVID-19, ALS, regenerative potential of fibroblasts, and why Zoom meetings are so tiring for the brain? I cover those topics and more below with recommended reads including papers and media items. Here’s last week’s recommended reads. Here’s to fibroblasts, which have regenerative activities Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing. This work from a team led by Jeff Biernaskie was published in Cell Stem …Read More

4 min read

Why is former Texas Governor/Trump Energy Secretary Rick Perry plugging unproven stem cells from a clinic firm called Celltex for COVID-19 prevention on Fox News? Perry follows in Giuliani’s footsteps? And more generally, what is it with conservative politicians promoting unproven therapies for COVID-19 and in particular stem cells for the novel coronavirus disease? First, we had Rudy Giuliani plugging what he called “stem cells” for COVID-19 on his webcast. This actually turned out to be natural killer (NK) cells, which are not stem …Read More

5 min read

The term Regenerative Medicine covers so much biomedical science these days including everything from just about any kind of cell therapy (not just stem cells) to CRISPR gene editing, and with the the COVID-19 pandemic, it seems this umbrella use of the term now includes potential treatment of viral illnesses. It can be hard to keep track of it all. I’m regularly doing a kind of “regenerative medicine” digest these days to help. Today’s post is just such an aggregate with a focus on …Read More