January 25, 2021

The Niche

Trusted stem cell blog & resources

chemical reprogramming

1 min read

Sheng Ding’s lab reports today in Cell Stem Cell (you can read it here) that they have replaced all genetic factors in a new iPS cell reprogramming method except Oct4. The other factors were replaced by chemical compounds. Thus, we continue a major transition in the iPS cell field away from genes and toward chemicals. This work is very exciting. Even with the advent of totally RNA-based iPS cell formation, progress toward a completely chemical approach is quite important. Many believe that an entirely …Read More