August 6, 2020

The Niche

Knoepfler lab stem cell blog

CRISPR designer babies

4 min read

A Russian Scientist named Denis Rebrikov told Nature and then other media including NPR last week that he plans to make CRISPR babies. In other words, babies with heritable genetic modifications. I don’t doubt that Rebrikov (pictured in ResearchGate image) might want to do this nor that he might try it, but rather I’m writing this post to point out how his statements including about why it’d supposedly be a good idea don’t withstand much scrutiny. What has Rebrikov said about his plan and …Read More

5 min read

Two prominent scientists, Robin Lovell-Badge and George Daley, have been amongst the most outspoken proponents of leaving the door open to heritable human genetic modification via CRISPR. While they each have articulated their reasons in somewhat different ways at times, their core reasons arguing in favor of future heritable CRISPR appear largely the same. In this post I tackle each of these arguments in favor of leaving the door open to “CRISPR babies” with science-based counterarguments. I also raise larger risks to going down …Read More

1 min read

Heritable CRISPR to be tried in humans sooner or later…or never? Will someone somewhere in the world try to use CRISPR gene editing or related technology to introduce heritable genetic changes into actual human beings in the next decade? I’m not talking about gene editing viable human embryos just for research which is already ongoing, but rather CRISPR’ing human embryos to then use to try to make babies who grow up to be adult humans with a specific genetic change. How likely is this? Take …Read More