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Knoepfler lab stem cell blog

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CRISPR human embryo

Stem cell predictions

Grading my twenty 2017 stem cell predictions

December 20, 2017 Paul Knoepfler 3

Each year I make a list of predictions for the year to come for the stem cell and regenerative medicine field. Then about a year later I grade myself on how I did as that year winds down. Here’s how […]

Human embryo CRISPR

Review of Mitalipov paper CRISPR’ing human embryos: transformative work on the edge

August 2, 2017 Paul Knoepfler 3

In the same way perhaps that some excited relatives or parents-to-be both gush and worry about a baby before it is even born, our field has been transfixed for a week by the Mitalipov paper on CRISPR’ing human embryos even […]

CRISPR human embryo

Paper on 1st use of CRISPR in normal human embryos: problems remain

March 9, 2017 Paul Knoepfler 1

The first report of the use of CRISPR gene editing in normal human embryos was published today as a short paper from a team in China. There have been rumors for over a year that more CRISPR human embryo papers were […]

ssistant Professor Fredrik Lanner

Interview with Fredrik Lanner who is CRISPR’ing healthy human embryos

September 26, 2016 Paul Knoepfler 2

In the past year there has been a great deal of attention given to the potential use of CRISPR-Cas9 for gene editing in human embryos. An important recent development, described in a new NPR article by Rob Stein, is the […]

embryo human

Where are all the new CRISPR human embryo papers?

August 25, 2016 Paul Knoepfler 4

Last year I heard from several sources that there somewhere between 3-5 unpublished manuscripts reporting the use of CRISPR gene targeting in human embryos being shopped around at various journals in addition to the one that had been published. Since that […]

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