CRISPR human

Why CRISPR baby production (if it happened) was unethical & dangerous

Jiankui-He-who-claims-CRISPR-baby-production

Reports are out that a scientist in China has been working to make a CRISPR baby for some time and supposedly has made twin genetically modified babies. I see this work as unethical and dangerous. Just a couple years ago when I published my book GMO Sapiens on potential use of CRISPR in a heritable manner …

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Science hype award for worst CRISPR headline

Daily-Mail-Science-Hype-CRISPR

Science hype is one of the more troublesome issues in our field today especially at its interface with the media, and unfortunately a ‘great’ example of that came this past week in a headline from the Daily Mail on the new CRISPR of human embryos paper from Kathy Niakan’s group in the UK. Although Niakan’s …

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Mulling over that Mitalipov human embryo CRISPR pub, still many questions

human-embryo-modification

What really happened at the DNA level in the experiments in that high-profile CRISPR of human embryos paper from a team led by Shoukhrat Mitalipov at OHSU? Is the team right that they successfully conducted CRISPR of human embryos to correct a mutant gene, as they reported in their Ma, et al. Nature paper? Or is the Egli, …

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Who leaked Mitalipov CRISPR human embryo paper?

CRISPR-human-embryo

The new CRISPR human embryo paper from Shoukhrat Mitalipov is stirring things up, but then there’s also the murky back story as to how the news of this as yet unpublished paper got leaked in the first place. The actual paper is still not out and from what I understand hasn’t even been officially released …

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Paper on 1st use of CRISPR in normal human embryos: problems remain

CRISPR-human-embryo-Tang-et-al

The first report of the use of CRISPR gene editing in normal human embryos was published today as a short paper from a team in China. There have been rumors for over a year that more CRISPR human embryo papers were coming including some using normal embryos. Here’s one and we can now expect more even …

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CRISPR Update: Patents, Embryos, & IPOs, oh my

Joanne-Manaster-

It’s been a busy few weeks for the CRISPR arena so I’ve made a CRISPR Update. I’ve listed below links to some commentaries and key developments.   Fun Video interview on Read Science! with Joanne Manaster on my new book on CRISPR in humans, GMO Sapiens. CRISPR: Pursuit of profit poisons collaboration, Nature piece by Jacob Sherkow …

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GOP Congress seeks ban on CRISPR of human embryos

statment_gene_editing-tech

GOP members of Congress want a ban on CRISPR of human embryos. They are moving to block genetic modification of human embryos using the new CRISPR gene editing technology. The new proposed spending bill part way through the approval process with the nugget of good news of a possible NIH spending boost after many years …

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