September 25, 2020

The Niche

Knoepfler lab stem cell blog

CRISPR hype

6 min read

By Guillaume Levrier Human germline editing has been done before. It will be done again in the future, as it is relatively easy to perform. No mechanism with the de facto ability to prevent it from being organized has yet been designed, let alone implemented. But the fact that germline editing has, can, and will happen again does not deprive anyone of their right to have an opinion on this capacity. The CRISPR Consensus symposium (see video below) set up at the Innovative Genomics Institutes …Read More

3 min read

Could potential associated cancer risks claw into CRISPR’s potential? The short answer from both previous and new data is that while CRISPR gene editing impacts the P53 pathway, which is involved in cancer along with having many other functions, this news is neither too surprising nor a fatal flaw, but some caution is warranted. CRISPR is many things including an exciting technology that my own lab uses a lot, but it isn’t and never will be perfect or somehow magical. When this week’s story …Read More

1 min read

Science hype deserves negative attention for the harm it does including both to science itself and to patients. I’ve seen two really egregious examples of hype lately in science headlines. First from the Washington Post comes a stem cell story with a very hype-ful title: Stanford researchers ‘stunned’ by stem cell experiment that helped stroke patient walk What the heck? This is a small study and the stunning event could be a placebo effect. The actual article by Ariana Eunjung Cha isn’t bad and has some …Read More