July 10, 2020

The Niche

Knoepfler lab stem cell blog


1 min read

Heritable CRISPR to be tried in humans sooner or later…or never? Will someone somewhere in the world try to use CRISPR gene editing or related technology to introduce heritable genetic changes into actual human beings in the next decade? I’m not talking about gene editing viable human embryos just for research which is already ongoing, but rather CRISPR’ing human embryos to then use to try to make babies who grow up to be adult humans with a specific genetic change. How likely is this? Take …Read More

2 min read

Day 2 of the Human Gene Editing Summit in DC (#GeneEditSummit) was quite interesting and added more depth to the meeting overall. For specific talks, see my two posts from yesterday here and here. Also see my top takeaways from Day 1. What were the top highlights of Day 2 of #GeneEditSummit? Somatic work. We shouldn’t only focus on germline human genetic modifications even if that is the most explosive issue. Yesterday we heard about striking developments in the arena of somatic/adult gene editing …Read More

1 min read

A few weeks back I started a poll focusing on whether people would have a designer baby if they could. With nearly 200 responses so far, the results are very mixed (see image). One conclusion from this I think is that we need more information on possible risks versus benefits. Another element here is that the poll, as one commenter pointed out, did not divide between health-related and enhancement motivations behind having the designer baby. I may do a future poll including that divide. …Read More