June 3, 2020

The Niche

Knoepfler lab stem cell blog

Daniel Paull

2 min read

Ready for some stem cell good news? It can be difficult at times in a cutting edge field like stem cells in terms of keeping upbeat about hopes of rapid translation to help patients with real, proven therapies. It takes a long time, money, dedication, and even a bit of luck for the researchers and biotech companies out there. It’s a challenging path with many possible roadblocks and landmines. For instance, I recently wrote about how many stem cell stocks are not doing well. …Read More

4 min read

Advances in therapeutic cloning reported in the past year have been very exciting. Somatic cell nuclear transfer (SCNT) can be used to produce very powerful human embryonic stem cells (ESC). These new cells are called NT-ESCs for short. Neither embryos nor reprogramming factors are needed to produce human NT-ESCs. See here, here and here for discussions of the pioneering papers reporting creation of NT-ESC including the first paper by the lab of Shoukhrat Mitalipov of OHSU, which I called the stem cell event of the year for 2013. Now that human NT-ESC are …Read More