September 27, 2020

The Niche

Knoepfler lab stem cell blog

Elizabeth Liz Parrish

1 min read

The myostatin gene has been getting quite a bit of attention lately. The buzz surrounds the idea of inhibiting myostatin either through gene therapy or via germline human genetic modification. In this way, some hope to create people with more muscle. Myostatin, which also goes by the acronym MSTN, has an inhibitory function on muscle. Inhibit and inhibitor of muscle and you should get more muscle, right? Data backs it up. Animals including humans with spontaneous mutations in myostatin have unusual musculature including increases in …Read More

4 min read

In a strange, but fascinating tale recounted by Antonio Regalado in an article over at MIT Tech Review, we hear the first claim of a do-it-yourself (DIY) gene therapy. The owner of a small biotech called BioViva, Elizabeth “Liz” Parrish, reportedly traveled from her home in Seattle to get an unapproved, experimental gene therapy in another country. The article pointed to a Reddit AMA that Parrish recently did where she discussed these events in the context of her interest in anti-aging efforts. Regalado is fairly …Read More