Feng Zhang

CRISPR baby moratorium grows likely with rising tide of support including from biotech

CRISPR-gene-edit-vs-mutation-1

Trying to make a CRISPR baby any time soon would be a really bad idea. How bad? Last December 3rd I penned a piece for STAT News arguing for a moratorium on the heritable use of CRISPR in humans. This potential future, radical application of “gene editing” is now often colloquially referred to as “CRISPR …

CRISPR baby moratorium grows likely with rising tide of support including from biotech Read More »

Trying to connect the dots on CRISPR baby story paints a dark, cloudy picture

connect-the-dots

When I was a little kid I played this game called “connect the dots” or “dot-to-dot”, where you draw a line from dot-to-dot in numerical order and at some point a picture starts to emerge. I think kids and even some adults still play this today. They even come in extreme versions with hundreds or …

Trying to connect the dots on CRISPR baby story paints a dark, cloudy picture Read More »

Movers & Shakers in Stem Cell & Regenerative Medicine Field

stem-cell-movers-and-shakers

Stem Cell & Regenerative Medicine field researchers move around to different places fairly often. It is interesting to note trends and also see who received what kinds of awards and such. Below is a list of some recent movers and shakers. George Daley got the ISSCR Public Service Award (you can see other ISSCR Awards here). …

Movers & Shakers in Stem Cell & Regenerative Medicine Field Read More »

Why UC Berkeley deserves the main CRISPR patent

statment_gene_editing-tech

Some months back a USPTO court issued a ruling that most interpreted as meaning the Broad Institute had won the so-called ‘CRISPR patent battle’ in the U.S. and that UC Berkeley, Jennifer Doudna, and Emmanuelle Charpentier had lost. Now this week Berkeley has appealed that ruling. It seems the odds are against Berkeley prevailing in its appeal, but frankly …

Why UC Berkeley deserves the main CRISPR patent Read More »

Does Word Cloud of Lander’s Heroes of CRISPR Text Suggest Bias?

Lander-cloud-2

Eric Lander’s recent piece in Cell on The Heroes of CRISPR has sparked strong reactions that are mostly critical and have argued that the article is biased. I’m going to weigh in with my own thoughts at some point later, but I thought it would be interesting to try a word cloud-based text mining of the Lander …

Does Word Cloud of Lander’s Heroes of CRISPR Text Suggest Bias? Read More »

Patent expert weighs in on CRISPR dispute between UC & Broad

CRISPR-patent-dispute

The patent dispute on CRISPR between UC/Jennifer Doudna and The Broad/Feng Zhang has been the subject of major attention including in a recent piece on Stanford Center for Law & Biosciences Blog. There is a lot of confusion over this important CRISPR dispute so I turned to a patent expert for their take on this via an interview …

Patent expert weighs in on CRISPR dispute between UC & Broad Read More »

Weekend science reading: fantastic found links including on CIRM

glioblastomaWiki

David Jensen reports on the future of CIRM as a “beautiful machine”. CIRM funds brain cancer research in a big way: Funding a clinical trial for deadly cancer is a no brainer. Glioblastoma is a fatal tumor that needs new clinical approaches so this is exciting. One of the goals of my lab is to find new …

Weekend science reading: fantastic found links including on CIRM Read More »

Doudna most deserving of CRISPR Cas9 patent, says poll

CRISPR-Patent-Poll

With more than 250 votes cast, Jennifer Doudna is leading by a decisive margin in a poll asking who deserves the patent for use of CRISPR-Cas9 as a tool. Feng Zhang got only just over half the votes of Doudna. Another take home message from this poll is that a sizable minority–almost one in five– said …

Doudna most deserving of CRISPR Cas9 patent, says poll Read More »

5 new cool papers on CRISPR Cas9 gene editing

Cas9-NHEJ

CRISPR Cas9 is a relatively new, powerful approach to gene editing and genetic modification more generally. In the relatively short window of time in which this technology has been widely available for gene editing applications it has already evolved rapidly to become more powerful. Here are some new papers of interest on this technology. With …

5 new cool papers on CRISPR Cas9 gene editing Read More »