gene editing

Mixed messages on CRISPR babies from National Academies versus their experts: a look at new Science piece

National-Academy-CRISPR-Baby-article

Three national academy leaders have a new opinion piece in Science on what the community needs to do next regarding human germline editing now that we are most likely in the CRISPR babies era. Some of us have been wondering what the Academies and their empowered experts really think about this issue and what they …

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He Jiankui didn’t really gene edit those girls; he mutated them

CRISPR-gene-edit-vs-mutation-1

Did Chinese researcher He Jiankui really CRISPR gene edit the CCR5 gene in two embryos producing twin baby girls? In my opinion the answer is “no”, but probably not for the reason you might think at first. He proclaims gene edits He claimed he had made twin baby girls with “gene edits”, which I feel is unethical …

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Mulling over latest CRISPR tumult, this one from Nat Biot pub on DNA lesions

CRISPR-dart-board

If it seems to you like dramatic cautionary tales about CRISPR accompanied by all sorts of media are coming at us more frequently, it’s not your imagination. In the latest yesterday, it was reported in a new paper led by Allan Bradley that CRISPR-Cas9 results in sometimes large-scale chromosomal lesions at or even away from the …

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CRISPRcon guest post: Hope for a brighter future

Anna-Everette

By Anna Everette “In our society, we have an addiction to vertical genetic transmission. It’s called sex and having a child who looks like you”. This was perhaps the most memorable quote from the event’s keynote speaker, Greg Simon, Director of the Biden Cancer Initiative. It also happens to highlight the most compelling reason to …

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NgAgo a-go-go: main bullet points on upstart CRISPR challenger

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The gene editing technology CRISPR has been arguably the top story in the biomedical world in the last two years, but going forward there is a CRISPR challenger in upstart gene editing technology NgAgo. For more background on NgAgo and the key first published paper on its genetic modification characteristics see my post here.  In the comments on that …

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CRISPR Cas9 Gene Editing Tech Will Revolutionize Biology

Why is CRISPR Cas9 gene editing such a big deal? Imagine being able to make mutations in any gene you wanted say in stem cells in a relatively simple, quick and affordable fashion? Sounds exciting, huh? Every so often a new kind of technology comes along in the biomedical sciences that is a true game …

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