September 29, 2020

The Niche

Knoepfler lab stem cell blog

genetic infection

4 min read

Gene drive is a powerful, emerging genetic technology that can force genetic modification into an entire population. For more background on gene drive you can read my previous post. It’s a very exciting, but potentially dangerous technology with sizable possible risks. Recently I had an intriguing conversation with leading geneticist Harmit Malik on gene drive. What makes nuclease-driven gene drive so exciting for genetics? HM: It is very attractive because of its power, speed, and simplicity for genetic studies. As you know from your mouse …Read More

4 min read

Scientists studying genetics are both excited and worried about a powerful, new technology called “gene drive“. Some have been raising serious concerns about gene drive and in certain cases calling for proactive regulation, which is unusual in science. This method is so powerful because it is designed to induce genetic changes in an entire population in a relatively extremely short period of time compared to natural evolution and is self-propagating. The most talked about form today is a type powered by CRISPR-Cas9 gene editing …Read More