George Daley

CRISPR baby moratorium grows likely with rising tide of support including from biotech

CRISPR-gene-edit-vs-mutation-1

Trying to make a CRISPR baby any time soon would be a really bad idea. How bad? Last December 3rd I penned a piece for STAT News arguing for a moratorium on the heritable use of CRISPR in humans. This potential future, radical application of “gene editing” is now often colloquially referred to as “CRISPR …

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Counterpoints to Lovell-Badge & Daley’s CRISPR baby rationales

CRISPR-baby

Two prominent scientists, Robin Lovell-Badge and George Daley, have been amongst the most outspoken proponents of leaving the door open to heritable human genetic modification via CRISPR. While they each have articulated their reasons in somewhat different ways at times, their core reasons arguing in favor of future heritable CRISPR appear largely the same. In …

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Woman grows nose tumor in spine after stem cell injection

New-Nose

Clare Wilson over at the NewScientist has reported the case of a woman given an experimental stem cell treatment in Portugal for a spinal cord injury who later developed a strange tumor consisting of nose tissue. I highly recommend going over to that site and reading her excellent article. What’s the deal with this case? The woman was …

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Summary of George Daley talk on iPS cells today in Seattle

The best talk today was the keynote address by Dr. George Daley focused mostly on iPS cells. Dr. Daley is one of the world’s experts on iPS cells and pluripotent stem cells more generally. He covered many interesting elements of the iPS cell field including the genetic mutations that seem to occur during the reprogramming …

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iPS cells coming into focus: not quite so similar to ESC after all

FaviconIPSCELL

Update in 2020: It seems now after all these years that the consensus in the now more mature field is that IPSCs and ESCs are nearly identical in most cases, and both have some of the same translational challenges such as teratoma-forming activity. It’s interesting to read this post from nearly 10 years ago and …

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