September 30, 2020

The Niche

Knoepfler lab stem cell blog

Geraldine Dawson

7 min read

A solid new, blinded placebo-controlled Phase II study from a Duke team clearly shows no benefit of cord blood for autism. Surprisingly, the team has said they are encouraged by the results. As a result, they apparently will continue this kind of work anyway despite their data. In contrast, I see the data as a probable stop sign. Few have been as upbeat over the years as this Duke team about the idea of cord blood for autism spectrum disorder. I have been one …Read More

6 min read

Stem cells for autism? After watching this area for many years, I’m not sure there’s any “there there”. There are logical reasons to think that certain stem cells might help many specific diseases, but in my view autism isn’t likely to be one of them. I hope I’m wrong, but today at least in 2018, it’s not looking promising. To be clear, I’m not talking about indirectly using stem cells for non-clinical trial research to provide conceptual and translational insights into autism spectrum disorder, …Read More

2 min read

What’s the scoop on stem cells for autism? Could stem cells make a real difference for autism patients and their families? CNN has a big, high-profile new article out today on the Duke stem cell trial for autism that has been ongoing for a while and I’m wondering how good a job CNN did on this one. Too often media over-hype stem cells and this includes for autism. I’ve covered the Duke trial before here and here, which is run by Dr. Joanne Kurtzberg, a scholar in …Read More

3 min read

Is there real promise of stem cells for autism? At this point the jury remains out on that question, but a growing number of kids are nonetheless getting such “treatments” at for-profit dubious clinics. Academic clinical researchers are interested in this area as well. Still, the potential use of stem cells to treat autism is a highly controversial area even in a clinical trial setting. Today it was announced in a piece on the website of the Simons Foundation Autism Research Initiative that a dramatically …Read More