September 29, 2020

The Niche

Knoepfler lab stem cell blog

GMO people

3 min read

Over at Practical Ethics they are calling for an almost Spock-like, emotion-free, and logical approach to the topic of heritable human genetic modification. Sounds good in principle, right? Well, unfortunately it fails in execution in their essay. The authors of “Editing the germline – a time for reason, not emotion” seem to include Chris Gyngell, Tom Douglas, and Julian Savulescu. It is notable that this Practical Ethics piece itself has an unmistakable bias toward allowing human germline modification to proceed unfettered by what they view as …Read More

2 min read

Discussion of concerns over heritable human genetic modification has spiked in 2015. This dialogue is a good thing, but is it in a sense too late? Are genetically modified (GM) people a foregone conclusion? Rumors are swirling that upwards of four papers reporting production of GM human embryos are in various stages of review at high-profile journals, sparking a sense of urgency for some kind of steps to deal with this new reality. Could these papers report germline correction of the CTFR mutation in cystic fibrosis …Read More

8 min read

What’s Cambrian Genomics? With rapid advances in genomics, gene editing, and methods to reproduce life in the lab such as cloning, today creating genetically modified organisms (GMOs) has never been easier. While there have been of course loads of discussions of GMOs in the past, we are entering a new era of what one might call DIY GMOs, when everyday people outside of a lab (possibly enabled by biotech companies) might be able in theory to create new GMOs themselves. This could in the …Read More