November 24, 2020

The Niche

Knoepfler lab stem cell blog

H3.3 stem cells

4 min read

A relatively newly recognized, important player in the stem cell field is a molecule called histone variant H3.3. Histones are key components of chromatin with integral roles in regulating almost all aspects of cell behavior through orchestrating functions such as transcription and chromosome segregation. My lab has just (April 9) published new studies on histone H3.3, the first of their kind on the endogenous histone H3.3 protein in mammals. The work was supported by CIRM and NIH. Much of our work was based on …Read More