September 30, 2020

The Niche

Knoepfler lab stem cell blog

Harvard Betatrophin

2 min read

UPDATE: Unfortunately the Betatrophin paper discussed here originally back in 2013 has now largely been proven to have come to incorrect conclusions (for more read this). Today Harvard Stem Cell Institute (HSCI) reported the discovery, in a paper in Cell by Harvard Professor Doug Melton, of a powerful new hormone called Betatrophin that can stimulate growth of beta cells in vivo. Beta cells are the type of cell that are lost in Diabetes. From the HSCI press release: The hormone, called betatrophin, causes mice …Read More

3 min read

Harvard Stem Cell Institute (HSCI) is making a big announcement today about stems, the biggest they say in their almost decade-long existence. Last night I speculated/predicted some possible announcements. Today I’m betting they will announce the discovery of a novel factor called Betatrophin. More on Betatrophin in a minute, but first why do I think it most likely that their announcement is on it? In reality, I’m still not sure, but I suspect it is Betatrophin because I was alerted to a perhaps premature …Read More