hESC

Perspectives on Pedersen Lab Human-Mouse Chimera Paper

human-mouse-chimera

A new Cell Stem Cell paper by Victoria L. Mascetti and Roger Pedersen on human-mouse chimera modeling is quite interesting and important. I really enjoyed this short paper, but I do have a reservation about one way that it is being interpreted. The authors show that human pluripotent stem cells (hPSC) including induced pluripotent stem cells …

Perspectives on Pedersen Lab Human-Mouse Chimera Paper Read More »

Michael Cea ISSCR chat with Jeanne Loring on stem cell field

Lewy_Body_alphaSynuclein

By Michael Cea Jeanne Loring of the Scripps Research Institute in La Jolla, California kindly sat down with me at the ISSCR annual meeting for a broad discussion of her history, views on the field and developments in the science. I found Jeanne a refreshing character, as I did a number of others I was fortunate to …

Michael Cea ISSCR chat with Jeanne Loring on stem cell field Read More »

Supreme Court Rejection of WARF hESC Patent Challenge Discussion

james-a.-thomson-214x3001

The challenge to the WARF/Jamie Thomson patents/IP on human embryonic stem cells (hESC) is at an end. The US Supreme Court declined to hear the case. Earlier, the USPTO had turned down the challenge leading to a winding road in the courts. What do you all think of this stem cell IP challenge and the …

Supreme Court Rejection of WARF hESC Patent Challenge Discussion Read More »

Stem cell field stumbles on cloning dialogue

circle-the-wagons-cover-tbnl1

We had the big news last week that for the first time ever, human embryo cloning (aka “therapeutic cloning”) worked to produce apparently normal embryonic stem cells. I posted about it a few times here, here, and here. I have tried my best to be factual, open minded, and realistic about the issues. Frankly, the …

Stem cell field stumbles on cloning dialogue Read More »

5 human therapeutic cloning talking points dissected

Knoepfler-art-Human-Cloning

Yesterday’s report of human therapeutic cloning to make embryonic stem (ES) cell lines is a big deal. I support the work and I believe it is very important. People’s reactions to it vary wildly depending on their agendas of course. This post is a no-nonsense overview of the main points. My overall point. This is …

5 human therapeutic cloning talking points dissected Read More »

Human cloning successfully makes embryonic stem cells

For the first time ever, scientists have successfully used somatic cell nuclear transfer (SCNT) via the process of therapeutic human cloning to generate normal human embryonic stem cells (hESC). Recall that there are two kinds of human cloning: therapeutic (which is reported in the new paper discussed in this post) and reproductive, which is making …

Human cloning successfully makes embryonic stem cells Read More »

Which pluripotent stem cell type is most clinically promising? Take our poll

Adult stem cells are very powerful and important, but it is basically now an established fact that pluripotent stem cells will have important, unique applications in the clinic. Adult stem cells are not a panacea and we need pluripotent stem cells too. But what is the most promising type of pluripotent stem cell? Take our …

Which pluripotent stem cell type is most clinically promising? Take our poll Read More »

Analysis: what does the federal court embryonic ruling really mean & what’s next?

Knoepfler lab stem cells

Today the US Federal Court of Appeals via a 3-judge panel ruled in favor of continued NIH funding of human embryonic stem cell research (hESCR). The ruling is a setback for pro-life extremists trying to shut down a very promising avenue of stem cell-based regenerative medicine with their lawsuit. It’s a good day for the …

Analysis: what does the federal court embryonic ruling really mean & what’s next? Read More »