November 30, 2020

The Niche

Knoepfler lab stem cell blog


2 min read

A new Cell Stem Cell paper by Victoria L. Mascetti and Roger Pedersen on human-mouse chimera modeling is quite interesting and important. I really enjoyed this short paper, but I do have a reservation about one way that it is being interpreted. The authors show that human pluripotent stem cells (hPSC) including induced pluripotent stem cells and embryonic stem cells (hIPSC and hESC, respectively) are pluripotent in vivo during early development. They come to four main conclusions as outlined in their highlights section: •hiPSCs and …Read More

5 min read

One of the most exciting developments in the biomedical sciences in 2014 was the announcement of the new Allen Institute for Cell Science. This new institute, which will be focused on cell biology, received $100 million in funding from high-tech pioneer and philanthropist, Paul Allen. I am very curious about how the institute will tackle cell biology from a new angle so I invited the inaugural Director, Dr. Alan Rick Horwitz, to do an interview and he kindly agreed. Paul: It sounds as though a …Read More