November 23, 2020

The Niche

Knoepfler lab stem cell blog

Hiromitsu Nakauchi

3 min read

A new paper focused on human and other chimeras just came out today in Cell reporting a number of findings, but most strikingly successful generation of human-pig chimeras in utero. The paper, entitled, “Interspecies Chimerism with Mammalian Pluripotent Stem Cells” describes various chimeras including mouse-rat ones, although those have previously been reported. This work comes from a team led by Juan Carlos Izpisua Belmonte including first author Jun Wu, and also with important contributions from Pablo Ross’s lab here at UC Davis The big news …Read More

2 min read

Chimeras are one of the more controversial and fascinating areas of human stem cell and early embryo research. The notion of a chimera traces back thousands of years to creatures that were mixtures of various animals including humans in some cases. What about a real human chimera embryo? Today, chimera research has the potential to make major advances in our knowledge and even biomedical treatments such as through human organ creation within animal chimeras. However, human chimera research is intensely divisive amongst society more …Read More

1 min read

One of the best stem cell meetings each year is the World Alliance Form San Francisco (WAFSF) stem cell conference. It brings together in San Francisco many of the very best stem cell researchers from around the world doing the most cutting edge translational research. You should go! The speakers include Shinya Yamanaka, Masayo Takahashi, Michael Werner, Roman Reed, Susan Solomon, Jonathan Thomas, Edward Lanphier, Emile Nuwaysir, Hiromitsu Nakauchi, and many more top scientists. You can see the amazing program here and register here. …Read More

3 min read

The World Alliance Forum held a really great meeting yesterday in SF about the future of stem cells. Below, Johnathon Anderson has a great guest post summarizing the meeting. The collective brain power in the room was pretty staggering. The meeting brought together stem cell leaders from academia, industry, startup incubators and funding agencies. The purpose of the meeting was three fold: 1.) foster collaboration between US and Japanese stem cell researchers, 2.) facilitate interaction between academics and industry, and 3.) to honor Dr. Shinya …Read More