September 29, 2020

The Niche

Knoepfler lab stem cell blog

Hisashi Moriguchi

4 min read

Could He Jiankui have faked part or all of his CRISPR babies story? If so, how? Why? Or to put it another way, almost everyone seems to be assuming the story is real, but should we be more skeptical? Should we flip things around and assume the story isn’t entirely kosher until proven otherwise? I once said that the CRISPR field feels like it moves in dog years (very fast!) Consistent with that warp speed, the last 2 weeks have felt more like months. In …Read More

3 min read

I’m getting some heat from some stem cell folks who think I should not have blogged about the Moriguchi iPS cell transplant case. Their argument seems to be it would have been preferable to either (A) not blog about the story at all or only minimally so fewer people would know about it or (B) let professional journalists handle it in a more “measured” manner. I don’t really buy either argument. Let’s go over the timeline. On October 10th, Hisashi Moriguchi reportedly presented his …Read More

3 min read

My phone has been ringing and my email flowing at an even faster rate than usual over this still breaking story of the reported transplant of iPS cells into human patients by a Japanese scientist, Hisashi Moriguchi , who at some point was a visiting scientist at Harvard, apparently no more recently than 12 years ago. The story is confusing and seems to be rapidly changing by the hour. The fundamental question that remains is did Hisashi Moriguchi transplant iPS cells into patients or not? …Read More