human CRISPR

Science hype award for worst CRISPR headline

Daily-Mail-Science-Hype-CRISPR

Science hype is one of the more troublesome issues in our field today especially at its interface with the media, and unfortunately a ‘great’ example of that came this past week in a headline from the Daily Mail on the new CRISPR of human embryos paper from Kathy Niakan’s group in the UK. Although Niakan’s …

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4 key reasons Mitalipov paper doesn’t herald safe CRISPR human genetic modification

CRISPR-dart-board

We can be confident that human genetic modification via CRISPR’ing of embryos soon will be safe and effective after that new exciting Mitalipov team paper, right? Wrong. The reality is far more complicated and interesting on the tech side. In a nutshell, I see the paper as a significant scientific, but not necessarily medical advance. …

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FDA chides US doc who genetically modified human embryo in reported 3-person IVF

John-Zhang-with-3-person-IVF-baby

The FDA sent a stern letter today to Dr. John Zhang, PhD, MD, the physician who last year created a genetically modified human embryo in the U.S. and then exported it to Mexico where he self-reported creating a genetically modified baby boy. While the genetically modified baby created in Mexico was reportedly seemingly OK, it’s not clear …

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CRISPR, human genetic modification, & a needed course correction

coverGMO-e1498086048321

Are designer babies made using CRISPR or other genetic modification technologies closer to reality today? If so, what exactly should we do about it? Researchers can use CRISPR to genetically modify just about any organism or its cells, but targeting humans is the subject of the most intense discussion including using CRISPR in the human germline …

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National Academies panel leaves door a crack open to future human genetic modification

Early-human-embryos

A National Academies panel on human genome editing chaired by Alta Charo and Richard Hynes released its report today. While it covered both somatic and germline (heritable) human genetic modification, the latter topic is far more contentious. You can see the National Academies summary of their report here. You can read the full report here. …

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Korean edition of my GMO book on human CRISPR is out

GMO-Sapiens-Korean

I got a package from my publisher and upon opening it I saw the Korean edition of my book GMO Sapiens on the potential use of CRISPR in humans. The English language edition can be purchased here at the publisher where you can get 35% using the discount code WS16XMAS35 until January 15th or here on Amazon. …

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New Paper on CRISPR of Human Embryos Highlights Serious Tech Problems

Human-embryo-CRISPR

A new paper was recently published on CRISPR of human embryos for genetic modification. I’ve got to read this publication more carefully, but here’s a quick initial take on this human CRISPR 2.0 study. The paper is Kang, et al. and is entitled “Introducing precise genetic modifications into human 3PN embryos by CRISPR/Cas-mediated genome editing”. …

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