I talked last year about human genetic modification by CRISPR with George Church a year ago. Now we’ve followed up with a long chat on this topic going into much more detail and with questions on recent developments. Each question is listed numerically and then there is a back and forth on that question with George and me before going on to the next question. Frameworks for managing human genetic modification 1. Paul: What do you think of my ABCD plan for handling human germline …Read More
A new paper was recently published on CRISPR of human embryos for genetic modification. I’ve got to read this publication more carefully, but here’s a quick initial take on this human CRISPR 2.0 study. The paper is Kang, et al. and is entitled “Introducing precise genetic modifications into human 3PN embryos by CRISPR/Cas-mediated genome editing”. This is only the second paper reporting genetic modification of human embryos. The first paper, also from China, created quite a stir last year and reported a lot of technical …Read More
I like Easter eggs, science and writing, and Easter is less than a week away. I also think that games and puzzles as well as contests where there are prizes are fun. In this spirit I’ve hidden a scientific Easter egg inside of my new book, GMO Sapiens. If you are the first to find it and notify me, I will give you a $250 prize. We are talking about a scientific Easter egg. Wikipedia defines this sort of Easter egg this way: “An Easter egg is …Read More
I just finished filming a segment for PBS NewsHour, their national nightly news show along with Jennifer Doudna. It will air tonight. Take a look. Gwen Ifill interviewed Doudna and me about CRISPR and human genetic modification. I’ve pasted the video in YouTube Above. You can read my interview with Dr. Doudna on The Niche here.