human germline gene editing

Nita Farahany Interview on Human Germline Modification: Defining A Road Forward

Nita-Farahany

The topic of heritable human genetic modification has been heating up recently. Prominent scientists, ethicists, and legal scholars have being weighing in, and there is a range of attitudes. Some favor a complete, moratorium including even lab work, while on the other end of the spectrum there are those who have a more liberal perspective. Many …

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Jennifer Doudna Interview on CRISPR, Human Gene Editing

Jennifer-Doudna

I’m doing a series of interviews with leaders in the field on human germline modification with the first interview in this series with George Church and today’s second in this series is a conversation I had with Dr. Jennifer Doudna, a pioneer in CRISPR-Cas9 technology. Doudna is a Professor in MCB and Chemistry as well …

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Hank Greely Human Germline Modification Post

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Hank Greely over at The Center for Law and Biosciences at Stanford Law School was one of the participants in the recent Napa meeting on approaches to human germline genetic modification. Hank was also one of the authors on the resulting position paper in Science with David Baltimore as first author (here). Now Hank, pictured below, …

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Lisa Ikemoto on Human Germline Genetic Modification

ikemoto-lisa

This guest piece on Human Germline Genetic Modification is by Lisa C. Ikemoto, Professor, U.C. Davis School of Law. I have been following the reports about genetic editing technology with concern. The fact that some scientists are calling for moratoria on gene editing of human embryos heartens me. Frankly, I had little confidence that any …

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Practical Plan for Managing Human Germline CRISPR

ABCD-Plan-Human-Germline-Modification

CRISPR Cas9 gene editing technology is a game changer on many levels both inside and soon outside the lab. There is a growing sense of urgency amongst biomedical scientists to take a proactive approach to current and future use of CRISPR gene editing technology in human germ cells and embryos. These concerns have been heightened …

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David Baltimore, et al. path for human germline engineering

human-germline-editing-policy

In a new perspectives piece in Science, Nobel Laureate David Baltimore and co-authors including Jennifer Doudna and George Church, chart a potential path forward for human germline engineering. See also accompanying Bioethics piece by Gretchen Vogel as well, “Embryo engineering alarm”. In the piece, entitled “A prudent path forward for genomic engineering and germline gene …

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ISSCR calls for moratorium on clinical application of human germline nuclear genome editing

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The International Society for Stem Cell Research (ISSCR) just now released a new policy statement on human germline gene editing. The statement calls for a ban on clinical application of human germline gene editing technology. Here is the brief summary statement at the beginning: The International Society for Stem Cell Research calls for a moratorium on …

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