human GMO

New Herbert lab Nature paper reinforces mitochondrial replacement Achilles heel

Herbert-mitochondria-Nature-paper

Today a new Nature paper from Dr. Mary Herbert’s group in the UK has found a key problem with mitochondrial replacement therapy that fits with data from others. The goal of preventing mitochondrial disease using various kinds of genome transfer technologies is a noble one, but mitochondrial replacement therapy has faced a number of technological …

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UK should freeze mitochondrial replacement as Egli paper ID’s serious problem

Egli-genetic-drift-paper

An important new Cell Stem Cell paper from Dieter Egli’s lab points to an inherent, serious problem with so-called 3-person IVF or mitochondrial replacement technology that warrants putting an immediate hold on all efforts to use it in humans. I have pasted the graphical abstract from the paper below. For years a few of us scientists and …

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Proposed Moratorium on Genetic Modification of Human Germ Cells

sperm-and-egg

One of the hottest topics in the biomedical world in 2015 is heritable human genetic modification including via germ cells. There is an unsettling sense that genetically modified human germ cells and eventually GMO human beings are likely coming even if science and society are not ready for it. There are a hodgepodge of laws against human …

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Monday, March 2: My Reddit AMA on 3-Person IVF – Mitochondrial Transfer

reddit-logo

On Monday, I’ll be doing another Reddit AMA, this time on 3-person IVF also known as 3-parent IVF, mitochondrial transfer, 3-parent babies, etc. You can see the upcoming AMAs including mine listed in the right sidebar here. Mine will start at 10AM PST/1PM EST. I hope to discuss with a wide audience all the key …

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UK OKs 3-Person IVF: Perspectives

3-person-IVF2

With the House of Lords vote yesterday, the UK officially became the only country in the world to have legalized human genetic modification via 3-Person IVF. The point of this “mitochondrial transfer” or “3-person IVF” technology is not directly to genetically modify humans specifically, but it still will lead to that result in any case. …

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Human GMO Method Given OK by UK Parliament in Historic Vote

human-GMO

The UK Parliament just voted to legalize the production of genetically modified human beings. To my knowledge, this is the first time in history that such a vote has given the green light to make GMO human beings in any country of the world. There are other hurdles before this method can actually be used including the …

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