September 25, 2020

The Niche

Knoepfler lab stem cell blog

human therapeutic cloning

4 min read

It was intriguing last week to read about another advance in somatic cell nuclear transfer (SCNT)-based therapeutic cloning of human embryonic stem cells (hESC). The first such work was published last year by Mitalipov’s group from OHSU. This second paper to produce so-called nuclear transfer hESC (NT-hESC) made the important advance to show that it could be done using adult and even old human somatic cells. This is a reproducible technology, which is very important. However, key challenges and concerns remain for human therapeutic cloning …Read More

3 min read

An international team of stem cell scientists has replicated human therapeutic cloning to make embryonic stem cells via somatic cell nuclear transfer (SCNT). The team was led by Drs. Dong Ryul Lee of CHA Stem Cell Institute in Korea and Robert Lanza of Advanced Cell Technology (ACT) and reported the advance in the Chung, et al. paper today in the journal Cell Stem Cell entitled “Human Somatic Cell Nuclear Transfer Using Adult Cells”. The cells expressed pluripotency markers (see Figure 1A at left) and …Read More

3 min read

There have been many interesting developments in stem cells in 2013, but to me the biggest event by far was the first ever successful somatic cell nuclear transfer (SCNT)-based human therapeutic cloning. This approach generated apparently genetically normal human embryonic stem cells (hESC), an astonishing accomplishment. There are two kinds of human cloning: therapeutic and reproductive. The latter is making an actual new person with an identical genome to an existing person. The latter has never been achieved, but some of us are worried it …Read More

2 min read

Human cloning is not so far-fetched any more.  Cloning of the Star Wars variety where new copies of people (although they would be babies, not adults of course at first) are produced is something I believe that we’ll see in the next 1-2 decades. Why would anyone bother to clone? Fame. Money. Vanity. There are many reasons, all bad in my opinion. Then there is the possibility that human cloning could produce babies for infertile couples. Should human cloning be allowed in the future …Read More