September 27, 2020

The Niche

Knoepfler lab stem cell blog

Huntington’s Disease

5 min read

Some conditions like Huntington’s Disease are so bad and there are no treatments such that any bit of encouraging news can be cause for legitimate excitement, but at the same time things can go too far potentially, especially if there is news coverage not backed up by a published paper or some other definitive source of data. This kind of situation risks going from science over the line to hype. The splashy news a couple days ago that there may have been a “major …Read More

2 min read

This is the first post in a series focusing on stem cell advances related to specific diseases. Today we discuss Huntington’s Disease and a paper that came out yesterday in the journal Neuron that provides some significant insight into the mechanisms behind the disease. It is entitled: Huntingtin Is Required for Mitotic Spindle Orientation and Mammalian Neurogenesis Huntington’s Disease (HD) is a genetic disorder characterized by progressive neurological problems caused by neurodegeneration. The cause of HD was discovered to be mutations in a gene …Read More