September 26, 2020

The Niche

Knoepfler lab stem cell blog

induced pluripotent stem cells

5 min read

In the interview below I talk with Dr. Masayo Takahashi, who is leading a team conducting the first ever in-human clinical study based on iPS cells. The work began with patient enrollment on Aug. 1, 2013 in Japan. 1. Can you tell us a bit about your background? As an M.D./Ph.D. and ophthalmologist do you also see patients in addition to doing research? How did you first get interested in stem cells? Are your interests primarily in iPS cells? Yes, I have outpatient clinics in …Read More

3 min read

Stem cell technology is poised to wow the world with biomedical advances in the coming decades. Japan wants to lead the way, particularly with applications that focus on a relatively new kind of stem cells called induced pluripotent stem cells or iPS cells. Japanese researcher, Shinya Yamanaka, first reported production of iPS cells in 2006 in mice and in 2007 in humans. Japan has raced ahead of other countries and they appear to have the intellectual property rights and drive to do so. And …Read More

3 min read

In a shocker, Japan’s 2nd largest newspaper, Asahi Shimbun, published an editorial yesterday  saying that iPS cells are being pushed too fast to the clinic for economic reasons. The piece was bluntly entitled “Too much of a rush for clinical trials with iPS cells”. Asahi Shimbun, with a circulation of 10 million, is taking a bold step in questioning whether the iPS cell field in Japan might be moving too fast and the non-medical reasons behind that. They start off their piece with a bang …Read More

3 min read

Cellular Dynamics, the stem cell company founded by Dr. James Thomson, is filing for an IPO. Hat tip to David Jensen. The company, which will go under the stock symbol ICEL, is focused on iPS cell-produced products. They describe their portfolio as follows: Cellular Dynamics is developing and deploying a number of cell types derived from induced pluripotent stem (iPS) cells in additional to providing custom services to aid in life science research and drug discovery. If you recall, both Thomson and Dr. Shinya Yamanaka …Read More