July 11, 2020

The Niche

Knoepfler lab stem cell blog

iPS cells

2 min read

Adult stem cells are very powerful and important, but it is basically now an established fact that pluripotent stem cells will have important, unique applications in the clinic. Adult stem cells are not a panacea and we need pluripotent stem cells too. But what is the most promising type of pluripotent stem cell? Take our poll above to voice your opinion. A couple words about the possible challenges with each type. “Traditional” human embryonic stem cells (hESCs) have important potential, but with today’s technology …Read More

3 min read

Will intellectual property (IP) wars over patent rights to one of the most exciting new stem cell technologies hold back getting novel therapies to patients such as IPS cells? Unfortunately, it’s very possible. Induced pluripotent stem (iPS) cells are very cool stem cells made from non-stem cells through a process called cellular reprogramming. iPS  cells have essentially all of the same properties and powers as embryonic stem (ES) cells, but without the potential ethical complexity of utlizing a human blastocyst for their generation. Pretty amazing, …Read More

3 min read

There was a time, not so long ago, when the religious right hailed the discovery of induced pluripotent stem (iPS) cells. Headlines blared from the extreme right on the Internet such as, “Embryonic stem cells obsolete”. Even the same kind of thing, saying, “The stem cell debate is dead”. You see opponents of embryonic stem cells (ES cells) figured that the appearance of iPS cells, made from skin rather than blastocysts leftover from IVF, on the scene could be used as a propaganda weapon …Read More

2 min read

One of the most common myths is that stem cells are a zero sum game. What’s a zero sum game? It’s a dynamic where the overall good in a given situation or system stays the same. What this means is that in a zero sum game, if something is good for one person, it must be bad for someone else because the overall net situation does not change. There are real zero sum games in life, but the stem cell field is not one …Read More