IPSC clinical study

Takahashi team IPS cell vision paper marks major stem cell milestone

Takahashi-IPS-transplant

Ring the bell for a stem cell milestone. There’s been a whole lot of commotion about the NEJM article yesterday documenting the experiences of three women with macular degeneration who were blinded by non-FDA approved stem cell eye injections of fat stem cells at a business in Florida, but in the same issue of the journal …

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Nominations open for Stem Cell Person of the Year 2016 Award

Stem-cell-person-of-the-year-award

Nominations are open starting today for the Stem Cell Person of the Year Award for 2016. Please email me your nominations: knoepflerATucdavisDOTedu. This is a unique award as it is given to an individual who has taken risks to help others within the stem cell field and they based their actions on outside-the-box thinking. Another …

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Good stem cell news as Takahashi IPS Cell Trial to Resume

Masayo-Takahashi

Some good news today as the pioneering induced pluripotent stem (IPS) cell trial led by Dr. Masayo Takahashi will resume. This clinical study with a focus on macular degeneration has been on hold for quite some time due to regulatory changes in Japan. There had also been concerns over mutations in the 2nd patient’s IPS …

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Historic turning point for IPS cell field in Japan?

RPE-sheet_pr

As many of you know, the pioneering, first of its kind IPS cell clinical study in Japan has been suspended as I first blogged about here.2020 Update: I believe a version of this study is ongoing. In the comments section of that blog post there has been a helpful overall discussion that has involved Dr. …

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Masayo Takahashi (高橋 政代) on IPSC Trial for Vision

Monkey-stem-cell-RPEs

Masayo Takahashi (高橋 政代) on IPSC Trial for Macular Degeneration By Michael Cea Stem Cell Analyst & Advocate (editor’s note: piece was originally posted on Michael’s blog here; follow Michael on Twitter @msemporda) Having followed closely the developments in programs using pluripotent based therapeutics I was fortunate during ISSCR2015 to have the opportunity to sit down with …

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Landmark IPSC clinical study on hold due to genomic issue

IPSC-RPE-sheet

The pioneering induced pluripotent stem cell (IPSC) clinical study in Japan led by top stem cell clinical researcher Dr. Masayo Takahashi has been stopped reports the WSJ in Japan. This development is confirmed by other sources and in a PDF report by RIKEN (in Japanese here). One patient was transplanted in September 2014 with their own IPSC-derived …

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Stem Cell Person of the Year 2014: Masayo Takahashi (高橋 政代)

Monkey-stem-cell-RPEs

Congratulations to Masayo Takahashi (高橋 政代), MD, PhD, the winner of the 2014 Stem Cell Person of the Year Award. Dr. Takahashi received this award including the $2,000 prize for her exceptional achievements in stem cell research in 2014. She was selected as the winner from a stellar group of top 12 finalists this year. Takahashi leads …

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Yamanaka Interview on Clinical Use of IPSC

Dr.-ShinyaYamanaka

I invited Nobel Laureate Shinya Yamanaka to do an interview on the future of clinical translation of induced pluripotent stem cells (iPSC). He provides some intriguing new insights into the iPSC field and the broader stem cell arena. PK: The Takahashi Team’s active Clinical Study using iPSCs to make RPEs to treat Macular Degeneration has …

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