October 25, 2020

The Niche

Knoepfler lab stem cell blog

Jacob Sherkow

2 min read

Sometimes it seems like a bunch of stuff in one area, like with CRISPR this week, happens all of a sudden in science. A bunch of fairly high-profile gene editing pubs came out. They generated a lot of news reports. Other news in this arena popped up too, all within a few days. In vivo CRISPR editing with no detectable genome-wide off-target mutations over at Nature. In this context “no” is a really strong statement. Does the data back it up? See Figure 1a from …Read More

1 min read

It’s been a busy few weeks for the CRISPR arena so I’ve made a CRISPR Update. I’ve listed below links to some commentaries and key developments.   Fun Video interview on Read Science! with Joanne Manaster on my new book on CRISPR in humans, GMO Sapiens. CRISPR: Pursuit of profit poisons collaboration, Nature piece by Jacob Sherkow HIV Fights Off CRISPR Gene-Editing Attack. HIV adapts when CRISPR attacks. 2nd group CRISPR’s human embryos and things don’t go well. More Indels than precise gene edits, mosaicism and …Read More

2 min read

A lot has been going on in the CRISPR world. Here are some key CRISPR updates. Editas has filed the paperwork on the road to going public as a company. Such an IPO, should it come to fruition, could raise billions of dollars. Will the other CRISPR companies like Caribou and CRISPR Therapeutics follow suit? Simplistically, it seems like the first CRISPR IPO could get the lion’s share of investor money, but then there’s the patent thing hanging over all of this (see below) Patent …Read More