CRISPR Update: Patents, Embryos, & IPOs, oh my

It’s been a busy few weeks for the CRISPR arena so I’ve made a CRISPR Update. I’ve listed below links to some commentaries and key developments.Joanne Manaster

 

Fun Video interview on Read Science! with Joanne Manaster on my new book on CRISPR in humans, GMO Sapiens.

CRISPR: Pursuit of profit poisons collaborationNature piece by Jacob Sherkow

HIV Fights Off CRISPR Gene-Editing Attack. HIV adapts when CRISPR attacks.

2nd group CRISPR’s human embryos and things don’t go well. More Indels than precise gene edits, mosaicism and more.

CRISPR biotech Intellia strikes licensing deal with Regeneron, readies IPO. It’s interesting that there are these CRISPR IPO’s when the CRISPR patent situation remains entirely up in the air.

George Church versus Marcy Darnovksy on human modification in the WSJ

CRISPR/Cas9 Used to Create Knockout Chickens. Bock bock adoodle moo

New #CRISPR updates: Editas to go public, patent issues, dragons & more

CRISPR dragon

Dragon image from Wikipedia

A lot has been going on in the CRISPR world. Here are some key CRISPR updates.

Editas has filed the paperwork on the road to going public as a company. Such an IPO, should it come to fruition, could raise billions of dollars. Will the other CRISPR companies like Caribou and CRISPR Therapeutics follow suit? Simplistically, it seems like the first CRISPR IPO could get the lion’s share of investor money, but then there’s the patent thing hanging over all of this (see below)

Patent dispute rolls on. Jacob Sherkow over at the Stanford Law Blog dug into recent developments in the CRISPR patent battle. One big thing is the interference proceeding. A patent person I recently communicated with on this topic has some different views than Sherkow on much of this. I’m hoping to blog about that soon.

CRISPR on the news. If you missed it, Jennifer Doudna and I were interviewed by Gwen Ifill on the PBS News Hour last week (see below).

A BBC piece came out that was the subject of quite a bit of discussion on Twitter about whether CRISPR could be used to make a dragon. The item mentioned an article by Hank Greely and Alta Charo on CRISPR Critters (animals made using CRISPR) that had referenced the possibility of making a dragon. I tweeted that that was unlikely but that making a unicorn (adding a horn genetically to horses) was relatively more plausible.

A lively discussion followed including Carl Zimmer, Leonid Kruglyak, and Matthew Herper.