January 23, 2021

The Niche

Trusted stem cell blog & resources

Jan Nolta

4 min read

What’s new this week in terms of reads includes a stem cell/drug combo for diabetic wonderments healing, more documentation of patient harms from stem cell clinics, and a list of recommending papers. Adult stem cells/glaucoma drug combo promotes diabetic wound healing in mice From a team of my UC Davis School of Medicine colleagues led by Rivkah Isseroff, Jan Nolta, Athena Soulika, and Thomas Peavy we have in Stem Cells Translational Medicine this exciting new paper, Combination product of dermal matrix, human mesenchymal stem cells, …Read More

2 min read

With stem cells there’s always all kinds of developments and news every week or even every day. Here is an assortment in no particular order of some of the latest news including some across the spectrum including weird and sometimes stuff. The linked phrases are often the actual headlines of the media pieces. New CIRM Alpha Stem Cell Clinic offers HOPE for boys with deadly disease (article focused on our CIRM-funded Alpha Clinic here at UC Davis as part of our Stem Cell Program). Note …Read More

2 min read

Today’s piece is a stem cell movers and shakers post about individuals who have gotten awards, made moves, or otherwise made news recently. In some cases I’ve included relevant embedded tweets announcing the news. In case you’re wondering, the image at right is my attempt last year to make a graphic design that reflect both movers and shakers (the salt shaker). You can see my movers and shakers piece from mid-2017 here. I once met a scientist much earlier in my career who when …Read More

3 min read

Stem cell good news time…and more will be coming later this week. The stem cell and regenerative medicine world sometimes feels chaotic because so much is going on both on the positive and negative sides of things. There is a whirlwind of activity and developments, and a tendency sometimes within our arena to just avoid bad or complicated news. One mission of this blog is to try to cover the full spectrum of developments including difficult situations, but I also want to focus in …Read More

2 min read

So you’ve got a great draft paper on stem cells or regenerative medicine, but you’re wondering, “Which of the stem cell journals do I submit it too?” I get asked this question fairly often so I decided to do a post on it. Sometimes I ask myself this question about a paper we have nearly completed. A few years back a did a comprehensive (and sometimes humorous) post on stem cell journals including impact factors and I touched on the fact that there are …Read More

2 min read

What are stem cell exosomes? There’s been an explosion of interest in the biomedical world around a recently characterized cell-to-cell communication system that most cells use to talk to one another, including stem cells. In fact the first patient has been successfully treated in Germany with exosomes derived from mesenchymal stem cells for refractory graft versus host disease. This newly discovered communication system involves little bubbles called “exosomes” that cells secrete and pass on to their neighbors. This new cell communication system is akin …Read More

1 min read

The stem cell arena is a complicated universe with a whole range of things going on at any one time and there’s usually ample negative things, but not all is bad news. It’s interesting to regularly look specifically at the good stem cell news out there. Below is a look at some top pieces of good stem cell news and interesting recent papers. Ottawa to invest $20M in stem cell research  Piwi maintains germline stem cells and oogenesis in Drosophila through negative regulation of …Read More

4 min read

By Heather Main I moved to the San Diego from Australia in August 2015, and Paul asked me if I could write something on my first impressions of doing science in the US, as opposed to other countries I have worked/studied in (Australia, Scotland, Sweden and Singapore). If you look at the land size of Australia and consider that we have only 7% of the US population you will understand directly that funding and collaborative opportunities are not as easy to find. There’s probably …Read More

2 min read

A new stem cell clinical trial for Multiple Sclerosis (MS) in Canada is raising hopes amongst patients and researchers. According to the Ottawa Citizen, the trial will be led by Dr. Mark S. Freedman (pictured, photo from Ottawa Hospital), director of the multiple sclerosis research unit at The Ottawa Hospital and “The Canadian trials which are funded with a $4.2-million grant from the Multiple Sclerosis Society of Canada and the Multiple Sclerosis Scientific Research Foundation.” This clinical trial will use a type of stem …Read More

3 min read

By Paul Knoepfler Lakshmi Bharadwaj contributed to this article. See updated stem cell journal list for 2018 here. Important update on April 22, 2016. There are an increasing number of predatory journals out there and some use “stem cells” as a hook. This list is not an endorsement of these journals and in fact on a continuing basis if I hear concerns that some here are predatory I will delete them. I may also do a new post on this. With the excitement surrounding …Read More