October 20, 2020

The Niche

Knoepfler lab stem cell blog

Jeanne Loring

3 min read

By Jeanne Loring What can you do with cells that live forever and can make every cell type in the body?  The answer is: remarkable things, as new reports of clinical trials using cell types derived from pluripotent stem cells indicate. Pluripotent stem cells are either derived from embryos donated from IVF procedures (human embryonic stem cells- hESCs) or from cells provided by a person, usually blood or skin (induced pluripotent stem cells- iPSCs).  The stem cells are never used for transplantation; instead, they …Read More

3 min read

In Parkinson’s Disease patients develop neurological dysfunction as they lose a special kind of brain cell called dopaminergic (or dopamine) neurons. While a number of different approaches to this disease have been studied for decades, nothing has proven particularly successful in slowing its progression. As a result there has been a big need for novel thinking about how to tackle Parkinson’s Disease including via stem cells. One of the most exciting ideas has been to use human induced pluripotent stem cells (hIPSC) or human embryonic …Read More

3 min read

By Jeanne Loring Stem cells boldly go… Last week at the New York Stem Cell Foundation (NYSCF) conference at Rockefeller University in New York City, we announced our collaborative project to study the effects of microgravity on neurons derived from patient-specific induced pluripotent stem cells.  The press release is here. Susan Solomon, the CEO of NYSCF, announced the unprecedented collaboration:  NYSCF and San Diego’s Summit for Stem Foundation (Summit) are providing the cells and designing the experiment. Space Tango, based in Kentucky, developed the …Read More

3 min read

Even as some unproven, for-profit stem cell clinics promote themselves aggressively in many ways including now on TV, on the flip side lately we’ve seen more TV journalists covering questionable marketing by the clinics and negative patient outcomes. Today I saw that CBS This Morning, a national broadcast, had a fairly long TV segment on stem cell clinics. Even though the segment wasn’t perfect, it did a pretty good job overall. It was mostly focused on the case of patient Doris Tyler who alleges she …Read More