September 23, 2020

The Niche

Knoepfler lab stem cell blog

Jesse Gelsinger

1 min read

In the Steve Pinker interview that I posted this morning he was highly critical of noted bioethicist Dr. Arthur Caplan. I contacted Dr. Caplan out of fairness and balance to invite him to do a post/ask for any comment, etc. for this blog. Here is what he wrote: “Steven Pinker says; “But Arthur Caplan, the country’s most famous bioethicist, argued that the parents of such infants would be so consumed with grief that they could not truly give consent—the kind of paternalistic argument that is …Read More

13 min read

CRISPR-Cas9 gene editing technology is red-hot right now and I’ve been doing interviews with various thought leaders on it, which today includes Steven Pinker. This technology has great power for research in the lab and there are hypothetical transformative clinical applications of CRISPR too. The latter efforts could include experimental attempts at reversal of disease-causing mutations in one-cell embryos with the hope that they then grow into full-fledged, healthy human beings. Hypothetically CRISPR could also be used for pursuing human enhancement via germline genetic …Read More

6 min read

When are iPS cell-based therapies ready to be tested in actual people? It’s the million or perhaps even billion dollar question of today in the stem cell field. I realize that perhaps it is also a dangerous question, politically-speaking, for me to ask in a public forum, but patient lives as well as potentially the progress of the entire iPS cell field are at stake. So someone needs to start an open discussion about this topic. People are certainly talking about it behind the …Read More