September 19, 2020

The Niche

Knoepfler lab stem cell blog

Konrad Hochedlinger

6 min read

Today marks nearing the completion of a full circle for one of science’s biggest controversies: the STAP cell fiasco. Today STAP cells are completely refuted with the publication of two new papers in Nature and we know much more–with some notable gaps still–about what went wrong. In January of last year, an international team of collaborators from RIKEN in Japan and Harvard/Brigham & Women’s Hospital (including the lab of Charles Vacanti where the STAP idea reportedly originated) here in the US published two Nature …Read More

1 min read

Some diverse new stem cell papers worth a peek this weekend? Direct reprogramming hits crest: Generation of Multipotent Induced Neural Crest by Direct Reprogramming of Human Postnatal Fibroblasts with a Single Transcription Factor, Cell Stem Cell  Hormone receptors in prostate cancer cells versus stem cells: Concise Review: Androgen Receptor Differential Roles in Stem/Progenitor Cells Including Prostate, Embryonic, Stromal, and Hematopoietic Lineages, Stem Cells Remember Me-thylation: Dynamic and static maintenance of epigenetic memory in pluripotent and somatic cells, Nature A Variant Path to Pluripotency: Histone Variant H2A.X Deposition Pattern Serves as a …Read More

3 min read

Five legends and a blogger walk into a bar together. The bartender asks the first legend “What can I get for you?” The legend orders their drink. The bartender eventually serves up drinks to all five legends and turns to the blogger, “And what can I get for you?” The blogger replies, “Do you have Wi-Fi? “…..and a beer.” I’ve now been doing my stem cell blog for about 2 1/2 years. It started as an experiment and sort of took on a life of …Read More