August 6, 2020

The Niche

Knoepfler lab stem cell blog

Mahendra Rao

3 min read

A committee of the International Society for Stem Cell Research (ISSCR) did one heck of a document dump yesterday on stem cell policy, releasing a whole bunch of policy recommendations on stem cells and more. The torrent from ISSCR included a 37-page policy statement itself as well as several papers in top journals including the Lancet, Science, and Nature. This output was the product of the members of a special  ISSCR Task Force, whose members I have listed at the bottom of this post. Who …Read More

2 min read

Over the years some scientists including yours truly have expressed concerns about the possibility that mutations could crop up during the reprogramming process to make induced pluripotent stem cells (IPS cells or IPSC). How concerned should we be about IPS cell mutations? A cool new paper, Bhutani, et al, in Nature Communications from a team led by Jeanne Loring and Nicholas J. Schork presents data arguing against significant oncogenic mutations occurring during reprogramming to make IPSC. The authors summarize their findings this way: “Our results show a moderate …Read More

4 min read

It’s been a great couple days so far here at the World Stem Cell Summit in Atlanta. You can follow it on Twitter using the #WSCS15 hash tag. I first attended it 5 years ago in Pasadena. One of the special aspects of WSCS is it brings together diverse stakeholders in a way that just doesn’t happen elsewhere. For instance, you can have the FDA, patients, physicians, scientists, and funding agency people all in one room together. Some strong impressions so far include the …Read More

3 min read

Who might make a fantastic new CIRM President? The California stem cell community is abuzz with this question. This new President will not only lead CIRM today, but also in all likelihood will steer CIRM in its new incarnation after 2017, what I’ve called CIRM 2.0. At least that would be ideal. CIRM has posted a position/candidate specification document here including a summary of the position that includes this statement: The President of CIRM must be a nationally recognized leader with a vision, scientific credibility, and …Read More