Masayo Takahashi (高橋 政代)

Groundbreaking Organoid Vision Clinical Study: Takahashi Q&A

Mandai-et-al-Stem-Cell-Reports-2017

Clinical trials using organoids are still rare and a Clinicaltrials.gov search for such organoid work largely brings up in vitro studies. A new clinical study in Japan where organoid material will actually be transplanted into patients is causing a lot of excitement. Masayo Takahashi (高橋 政代) is a pioneer in stem cell-based clinical trial work …

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Highlights of ISSCR2017 – A Biomedical Engineer’s Perspective

Agnes-Soos

By Agnes Soos Amid the hustle and bustle of downtown Boston, nearly four thousand researchers and exhibitors gathered for the 15th Annual ISSCR Meeting. With presentations from over thirty plenary lectures, and dozens of others featured in concurrent sessions and the daily Innovation Showcases, there definitely was no shortage of exciting research to discover and …

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Japan IPS cell trial for vision to start in new incarnation

Masayo-Takahashi

It’s been a long road, but the first ever IPS cell clinical study in humans is starting up again in a new incarnation. You might say it has been regenerated in a novel form. Masayo Takahashi (高橋 政代) first started the pioneering IPS cell study a few years back in 2014, but it ended up …

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Yamanaka’s baby turns 10: ten IPS cell hot button bullet points

Nobel Laureate Shinya Yamanaka, the first to produce induced pluripotent stem cells

Has it really been 10 years since induced pluripotent stem cells (aka IPS cells or IPSC) came onto the scene in the stem cell field? Yes, it was a decade ago that now Nobel Laureate Shinya Yamanaka (山中伸弥) published that seminal Cell paper on reprogramming to make mouse IPS cells and then human IPS cells …

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At #ISSCR2016, $2,000 donation to Summit For Stem Cell patient group

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Something very unusual and positive just happened at this year’s ISSCR meeting. Every year in December I give out an award for the Stem Cell Person of the Year to the individual with the strongest positive impact in the stem cell field generated specifically from outside-the-box thinking and actions. Dr. Jeanne Loring was the recipient in …

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Good stem cell news as Takahashi IPS Cell Trial to Resume

Masayo-Takahashi

Some good news today as the pioneering induced pluripotent stem (IPS) cell trial led by Dr. Masayo Takahashi will resume. This clinical study with a focus on macular degeneration has been on hold for quite some time due to regulatory changes in Japan. There had also been concerns over mutations in the 2nd patient’s IPS …

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Parkinson’s IPS cell trial in Japan switching to allogeneic

Jun-Takahashi

What’s better for stem cell trials such as for vision loss or Parkinson’s Disease: allogeneic or autologous cells? In a major shift earlier this year, the induced pluripotent stem (IPS) cell trial in Japan for treatment of macular degeneration (MD) switched gears from using the patients’ own cells (called “autologous”) to using banked cells from …

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Stem Cell Person of the Year Award 2015: Nominations Open

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It’s time for The Niche 4th annual Stem Cell Person of the Year Award process to start. Please send me your nominations for the person you think had the biggest positive impact in the stem cell and regenerative medicine world in 2015. This award is unique in a number of ways. For example, anyone in …

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Masayo Takahashi (高橋 政代) Receives Ogawa-Yamanaka Stem Cell Prize

Masayo-Takahashi

The winner of the inaugural Ogawa-Yamanaka Prize is Masayo Takahashi, MD, PhD. According to the Gladstone Institute press release, “Dr. Takahashi was awarded the prize for her trailblazing work leading the first clinical trial to use induced pluripotent stem (iPS) cells in humans.” The prize, including a $150,000 cash award, will be given at a ceremony …

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Historic turning point for IPS cell field in Japan?

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As many of you know, the pioneering, first of its kind IPS cell clinical study in Japan has been suspended as I first blogged about here.2020 Update: I believe a version of this study is ongoing. In the comments section of that blog post there has been a helpful overall discussion that has involved Dr. …

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