Masayo Takahashi

Overview of IPS cell prospects for clinical impact

IPS-cell-clincial-trials-map

IPS cell research is a growing area of promise for regenerative medicine. These stem cells, also known as iPSCs or more formally as Induced Pluripotent Stem Cells, are engineered cells that are programmed to function the same way as embryonic stem cells. They can be differentiated into possibly any type of cell that is needed for …

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Masayo Takahashi (高橋 政代): exciting vision work advancing including with photoreceptors

Dr.-Masayo-Takahashi-高橋-政代.

Masayo Takahashi is a leading stem cell researcher doing translational and clinical research on vision. She’s doing pioneering work on using pluripotent stem cells as a basis for helping patients with vision loss such as due to macular degeneration. She won The Niche’s Stem Cell Person of the Year Award in 2014 and a number …

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Stem cell pioneer Masayo Takahashi (高橋 政代) leaves RIKEN

Masayo-Takahashi

In a surprise, Dr. Masayo Takahashi has announced that she has left RIKEN. Takahashi indicates she will be new President of a company called Vision Care, Inc. as part of the Kobe Eye Center. I’ve pasted a picture of Takahashi’s Tweet with translation more toward the bottom of the post. A big thanks to Piero …

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Autologous or Allogeneic: a stem cell question (guest post from Jeanne Loring)

stem-cells-and-development-parkinsons-disease

By Jeanne Loring What can you do with cells that live forever and can make every cell type in the body?  The answer is: remarkable things, as new reports of clinical trials using cell types derived from pluripotent stem cells indicate. Pluripotent stem cells are either derived from embryos donated from IVF procedures (human embryonic …

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3X recent stem cell & regenerative medicine good news

Stem cells spina bifida

In the past month or two there has been a steady stream of good news in the stem cell and regenerative medicine world. Here are three examples. Fate Therapeutics announced the first US IND for an induced pluripotent stem cell (IPSC)-related product. Its cleared product, FT500, is an off-the-shelf natural killer-based cancer immunotherapy. I expect …

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Japan conditionally approves new IPS cell-based heart study

Yoshiki-Sawa-IPS-cells-stem-cells-heart-diseease

Where do things stand with IPS cell translational research? The newest development is that regulators in Japan just have given conditional approval to an Osaka University team to an induced pluripotent stem (IPS) cell-based study for ischemic heart disease. For years IPS cell-based products have been on-again off-again in active clinical study for macular degeneration, work …

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Adverse event in IPS cell (ips細胞) trial for vision loss in Japan: initial perspectives

Takahashi-IPS-transplant

A team of researchers at RIKEN and Kobe City Medical Center reported at a press conference today a serious adverse event in a clinical trial participant receiving an induced pluripotent stem cell (IPS cell)-based therapy for vision loss. According to Japan Times and Yahoo! Japan (in Japanese), the patient in question in the IPS cell …

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20 predictions for stem cells & regenerative medicine in 2018

stem-cell-crystal-ball-300x3001

Every year I look into my stem cell crystal ball and make predictions for our field including regenerative medicine. Well, I don’t really look into a crystal ball, but I try to use a combination of what I’m hearing through the grapevine, stuff I’m reading, some info that is not yet in the public domain, …

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10 Stem Cell Person of the Year Award Finalists 2017

SCPOY2017-top-10-finalists

The votes are in and the community has picked its top 10 Stem Cell Person of the Year Award finalists. Both the 20 nominees and now the 10 finalists are a diverse group. The finalists include six women and four men, from five countries and four different continents. We also got votes from readers of the blog …

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