November 30, 2020

The Niche

Knoepfler lab stem cell blog

Mesoblast

5 min read

The term Regenerative Medicine covers so much biomedical science these days including everything from just about any kind of cell therapy (not just stem cells) to CRISPR gene editing, and with the the COVID-19 pandemic, it seems this umbrella use of the term now includes potential treatment of viral illnesses. It can be hard to keep track of it all. I’m regularly doing a kind of “regenerative medicine” digest these days to help. Today’s post is just such an aggregate with a focus on …Read More

10 min read

The idea of testing stem cells for COVID-19 may be music to the ears of some folks as an opportunity, but to me from the beginning it sounded mostly like a spaghetti on the wall road to trouble. There is buzz out there that some kind of stem cells or other cells will help with COVID-19. The reality is that that’s probably not going to happen. Even so, a whole range of people and firms are somewhat exaggerating and in a few cases outright …Read More

3 min read

  It’s been a busy week for the cellular and regenerative medicine space for COVID-19 news with some possible ups including for Mesoblast and some definite downs. Starting with the more positive media buzz with have Mesoblast. Mesoblast made COVID19 news “Thinly traded Mesoblast Limited (NASDAQ:MESO) rockets 51% premarket on average volume in reaction to its announcement of an 83% (n=10/12) survival rate in ventilator-dependent COVID19 patients who were treated with its allogeneic mesenchymal stem cell product candidate remestemcel-L within the first five days. Nine of the 10 …Read More

4 min read

Could two stem cell biotechs Athersys and Mesoblast help in the battle against the novel coronavirus disease COVID-19? Stem cells, ARDS, and COVID-19 I’ve already written two pieces about the idea of using stem cells to battle COVID-19 (here and here), the sometimes fatal disease that arises from infection with the novel coronavirus. Older patients and those with underlying conditions are those at greatest risk of severe disease that results in hospitalization, entry into the ICU, and in some cases death. One of the …Read More