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The Niche

Knoepfler lab stem cell blog

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mitochondrial genetic drift

Herbert mitochondria Nature paper

New Herbert lab Nature paper reinforces mitochondrial replacement Achilles heel

June 8, 2016 Paul Knoepfler 1

Today a new Nature paper from Dr. Mary Herbert’s group in the UK has found a key problem with mitochondrial replacement therapy that fits with data from others. The goal of preventing mitochondrial disease using various kinds of genome transfer […]

Egli genetic drift paper

UK should freeze mitochondrial replacement as Egli paper ID’s serious problem

May 19, 2016 Paul Knoepfler 1

An important new Cell Stem Cell paper from Dieter Egli’s lab points to an inherent, serious problem with so-called 3-person IVF or mitochondrial replacement technology that warrants putting an immediate hold on all efforts to use it in humans. I have pasted […]

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