mitochondrial genetic drift

New Herbert lab Nature paper reinforces mitochondrial replacement Achilles heel

February 1, 2021 / By / 1 Comment
Herbert-mitochondria-Nature-paper

Today a new Nature paper from Dr. Mary Herbert’s group in the UK has found a key problem with mitochondrial replacement therapy that fits with data from others. The goal of preventing mitochondrial disease using various kinds of genome transfer technologies is a noble one, but mitochondrial replacement therapy has faced a number of technological …

New Herbert lab Nature paper reinforces mitochondrial replacement Achilles heel Read More »

UK should freeze mitochondrial replacement as Egli paper ID’s serious problem

February 1, 2021 / By / 1 Comment
Egli-genetic-drift-paper

An important new Cell Stem Cell paper from Dieter Egli’s lab points to an inherent, serious problem with so-called 3-person IVF or mitochondrial replacement technology that warrants putting an immediate hold on all efforts to use it in humans. I have pasted the graphical abstract from the paper below. For years a few of us scientists and …

UK should freeze mitochondrial replacement as Egli paper ID’s serious problem Read More »