September 30, 2020

The Niche

Knoepfler lab stem cell blog

Multiple Sclerosis

3 min read

“HSCT Chicago Clinic Closing!” is the startling header in all caps on a patient-run Facebook page about a stem cell therapy clinical trial program at Northwestern University. What’s going on? Unfortunately, the promising field of hematopoietic stem cell transplantation (HSCT) for multiple sclerosis (MS) and other autoimmune diseases seems to have suffered an unexpected setback here. Dr. Richard Burt of Northwestern, one of the leading figures in the area of developing HSCT approaches for MS and other autoimmune disorders, is going on a sabbatical …Read More

5 min read

Stem cells for MS? How promising is that? A new paper gives stronger reason for hope, but unfortunately this story is more complex than it seems on first glance. New Paper The idea of using a stem cell-related approach to treat multiple sclerosis (MS) has been around for a long time holding major promise, but there hasn’t been much in the way of high-quality trial data out there in the published literature. A paper this week from the Richard Burt team at Northwestern (NW) …Read More

2 min read

A new stem cell clinical trial for Multiple Sclerosis (MS) in Canada is raising hopes amongst patients and researchers. According to the Ottawa Citizen, the trial will be led by Dr. Mark S. Freedman (pictured, photo from Ottawa Hospital), director of the multiple sclerosis research unit at The Ottawa Hospital and “The Canadian trials which are funded with a $4.2-million grant from the Multiple Sclerosis Society of Canada and the Multiple Sclerosis Scientific Research Foundation.” This clinical trial will use a type of stem …Read More

1 min read

Sometimes there is so much craziness and outright bad stuff going on out there around the world related to stem cells that we can lose sight of all the good news and encouraging developments as well. I think the new paper (Chen, et al.) from a team led by Drs. Lane and Loring is good news. I haven’t had time to fully read it yet, but it reports some encouraging results whereby human neural progenitors injected into the spine of mice with an experimental MS-like …Read More