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Mitalipov rebuts CRISPR pub critiques: strengthens case, but puzzles remain

Ma-et-al.-2018-Nature-FIgure-1

Remember that Shoukhrat Mitalipov lab paper on the use of CRISPR in human embryos? It’s back in the news. One of the biggest stories of 2017 centered on a Nature paper (Ma, et al., see my quick, initial review shortly after it was published here) from Mitalipov’s lab claiming both efficient repair of a disease-causing …

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4 key reasons Mitalipov paper doesn’t herald safe CRISPR human genetic modification

CRISPR-dart-board

We can be confident that human genetic modification via CRISPR’ing of embryos soon will be safe and effective after that new exciting Mitalipov team paper, right? Wrong. The reality is far more complicated and interesting on the tech side. In a nutshell, I see the paper as a significant scientific, but not necessarily medical advance. …

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