November 23, 2020

The Niche

Knoepfler lab stem cell blog

myostatin-related muscle hypertrophy

1 min read

The myostatin gene has been getting quite a bit of attention lately. The buzz surrounds the idea of inhibiting myostatin either through gene therapy or via germline human genetic modification. In this way, some hope to create people with more muscle. Myostatin, which also goes by the acronym MSTN, has an inhibitory function on muscle. Inhibit and inhibitor of muscle and you should get more muscle, right? Data backs it up. Animals including humans with spontaneous mutations in myostatin have unusual musculature including increases in …Read More