NgAgo versus CRISPR

New NgAgo protocol: helpful or more of a red flag?

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The supposed new gene editing technology NgAgo has had the scissors taken to it with basically no one able to get it to work conclusively and now the professor who led the work, Chunyu Han, has posted a new NgAgo protocol on the Addgene website. Updated NgAgo gene-editing: scientist posts revised protocol, with skeptical response …

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Controversy over CRISPR challenger NgAgo irreproducibility reported

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Does the new gene editing method NgAgo work or not? If not, what happened? The answers to both questions seem to depend on who you ask and what you read. As much as CRISPR has been the revolutionary in the genetic modification technology arena over past methods, could CRISPR itself in the next few years …

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NgAgo a-go-go: main bullet points on upstart CRISPR challenger

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The gene editing technology CRISPR has been arguably the top story in the biomedical world in the last two years, but going forward there is a CRISPR challenger in upstart gene editing technology NgAgo. For more background on NgAgo and the key first published paper on its genetic modification characteristics see my post here.  In the comments on that …

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Will new gene editing tech NgAgo challenge CRISPR?

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2020 Update: early NgAgo reports have been mostly discredited and there is doubt on its function as a gene-editing method. What could be better than CRISPR for gene editing? A new genetic modification technology called NgAgo has some researchers really excited. How does it compare to CRISPR? I’ll admit it that as a scientist who works on …

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