Oct4

OCT4-SOX DNA dance, PRC2, a noisy competition & more cell weekly reads

EMBO-J-2020-Fig-3b-Salazar-Roa-et-al

What’s new in the stem cell, cell therapy, and regenerative medicine world as well as biomedical science more generally including cancer? There’s quite a bit of news as reflected in media pieces and new pubs. Today’s post is focused on pubs that just came out. For last week’s recommended reads see here. Oct4-Sox2 Nucleosome Binding …

OCT4-SOX DNA dance, PRC2, a noisy competition & more cell weekly reads Read More »

Weekend reads include stem cell pubs, cancer link to heart disease, CRISPR babies & of course emu oil

stem-cells-heart-disease-trigger-immune-response

Here in the U.S. we just had our big Thanksgiving holiday, but science goes, stem cells keep growing and needing attention, and it’s another weekend chance to catch up on our paper reading. Here’s this weekend edition of recommended reads including news items and pubs. From Cell Stem Cell: Single-Cell Transcriptome Analysis of Uniparental Embryos Reveals …

Weekend reads include stem cell pubs, cancer link to heart disease, CRISPR babies & of course emu oil Read More »

CRISPR to make IPS cells: review of new Ding lab paper

Liu-et-al-Cell-Stem-Cell-IPS-cells-2018

CRISPR and IPS cells are two of my favorite things so when they come together as in a cool, new paper from Sheng Ding’s lab, I’m excited to read it and curious as to what the scoop is. Since 2006-2007 when mouse and human reprogramming were first reported, many different methods have been explored to …

CRISPR to make IPS cells: review of new Ding lab paper Read More »

Stem cells Sunday brunch of good news, fun links, & cool papers

Liao-et-al-Figure-2D

Enjoy! A Sunday brunch for the brain of science news, helpful links, and notable new papers including on stem cells. News and links CBER Director Focuses on Flexibility to Advance Regenerative Medicines Lab-Grown Blood Stem Cells Produced at Last Transplanted stem cells become eggs in sterile mice Maryland fund awards $8.5 million for stem cell research Positively good news from Asterias …

Stem cells Sunday brunch of good news, fun links, & cool papers Read More »

Quick journal club on IPSC anti-aging paper: cool, but outstanding questions

IPSC-anti-aging-paper

A new Cell paper from Juan Carlos Izpisua Berlmonte’s group has made headlines about anti-aging across the globe because it suggests that the four core induced pluripotent stem cell (IPSC) factors use by Shinya Yamanaka to make IPSC can reverse aging. I’ve pasted the graphical abstract from the paper below and done a quick journal club style …

Quick journal club on IPSC anti-aging paper: cool, but outstanding questions Read More »

Weekend Reads: Cool Papers, PubPeer, Jacob Hanna, & More

journals1

Here are some papers and news for weekend reads. What are you reading this weekend? What are your go-to stem cell journals? Hostile Takeover: Glioma Stem Cells Recruit TAMs to Support Tumor Progression by Yu Shi, Yi-fang Ping, Xia Zhang, Xiu-wu Bian in Cell Stem Cell. YAP1 Regulates OCT4 Activity and SOX2 Expression to Facilitate self-renewal and …

Weekend Reads: Cool Papers, PubPeer, Jacob Hanna, & More Read More »