June 4, 2020

The Niche

Knoepfler lab stem cell blog

OHSU

3 min read

What was the biggest news story of the year in the stem cell world? There have been many interesting developments in stem cells in 2013, but to me the biggest event by far was the first ever successful somatic cell nuclear transfer (SCNT)-based human therapeutic cloning. This approach generated apparently genetically normal human embryonic stem cells (hESC), an astonishing accomplishment. There are two kinds of human cloning: therapeutic and reproductive. The latter is making an actual new person with an identical genome to an existing …Read More

2 min read

We had the big news last week that for the first time ever, human embryo cloning (aka “therapeutic cloning”) worked to produce apparently normal embryonic stem cells. I posted about it a few times here, here, and here. I have tried my best to be factual, open minded, and realistic about the issues. Frankly, the stem cell field as a whole has done mostly a lousy job handling the human cloning dialogue sparked by the publication of the therapeutic cloning paper last week. It …Read More

3 min read

Yesterday’s report of human therapeutic cloning to make embryonic stem (ES) cell lines is a big deal. I support the work and I believe it is very important. People’s reactions to it vary wildly depending on their agendas of course. This post is a no-nonsense overview of the main points. My overall point. This is just one paper folks. It’s a turning point paper for the stem cell field to be sure, but there is a great deal to still be learned about this …Read More

3 min read

For the first time ever, scientists have successfully used somatic cell nuclear transfer (SCNT) via the process of therapeutic cloning to generate normal human embryonic stem cells (hESC). Recall that there are two kinds of human cloning: therapeutic (which is reported in the new paper discussed in this post) and reproductive, which is making an actual new person with an identical genome to an existing person. The latter has never been achieved, but some of us are worried it is coming sooner than most …Read More