July 7, 2020

The Niche

Knoepfler lab stem cell blog

Paolo Macchiarini

1 min read

Bulls-eye! Here are some stem cell weekend reads including both interesting new papers & news headlines. Of course, this week also had stem cell awareness day and I wrote about 10 key issues for the field for the coming 10 years! Weekend reads Papers Chromatin and Single-Cell RNA-Seq Profiling Reveal Dynamic Signaling and Metabolic Transitions during Human  A simple and versatile system for the ATP-dependent assembly of chromatin Genetic Evolution of Glioblastoma Stem‐like Cells from Primary to Recurrent Tumor MYC Controls Human Pluripotent Stem Cell …Read More

2 min read

A paper retraction is a major, painful step in science, but sometimes it is necessary and in the past few weeks we’ve seen news of two high-profile stem cell paper retractions. However, these retractions were handled entirely differently by those involved and were prompted by very distinct situations. Update: for some background on stem cell manuscript retractions more generally see from Retraction Watch here and from this blog here. In the case of a JCI stem cell manuscript retracted by Dieter Egli’s lab, a central problem …Read More

3 min read

Below are the 2016 stem cell predictions I made last year and their status now color-coded near year’s end. Green is right, orange is mixed bag, and red is flat out wrong. Overall, I did better than most past years with only having entirely blown it on four. Stay tuned later this week for my 2017 predictions, which looks to be a dramatic year in the field of stem cells and regenerative medicine. The Score Card on 2016 Predictions Another stem cell biotech acquisition by pharma …Read More

3 min read

Each December I make stem cell predictions for the coming year and I did that for 2016 where I made 20 predictions. At around mid year I do a checkup on how my predictions are doing halfway and that is the purpose of this post. Below are my predictions that I made in 2015 for stem cells in 2016 and my general sense in green of where they stand. Overall, I’m doing reasonably well, but I kind of wish I wasn’t because so many of these …Read More