January 18, 2021

The Niche

Trusted stem cell blog & resources

Parkinson’s Disease stem cells

4 min read

Today the FDA put an Arizona firm called R3 Stem Cell, LLC and its leader Dr. David Greene on notice that what they and 50+ affiliates centers are selling in the way of stem cells were not approved by the agency. R3 Stem Cell markets perinatal (birth-related) stem cell offerings on its website. There’s a lot of subtext in the FDA letter and accompanying PR, in my view none of it good for the company or its “centers of excellence.” The R3 website also …Read More

4 min read

For a long time at the end of each year, I’ve been making stem cell predictions for the coming year. Most often I’ve been making a “top 20” list of predictions and today’s post has my list for 2019. You can see how I did for 2018 here, which might have been my best year ever for predictions. We’ll see if I can match that here for 2019. I doubt it. However, I do think my prediction that 2019 will be the worst year …Read More

4 min read

By Jeanne Loring Last Tuesday I visited the FDA headquarters in Maryland, for a meeting called Public Meeting on Patient-Focused Drug Development for Huntington’s and Parkinson’s Diseases. The FDA holds about 6 meetings on different diseases each year, inviting patients and advocates to speak while a panel of FDA directors listens. The FDA representatives at this meeting included Billy Dunn and Eric Bastings, (Director, and Deputy Director, respectively, Division of Neurology Products [DNP], Office of New Drugs), Susanne Goldstein (Medical officer, DNP), and Theresa …Read More

25 min read

By Michael Cea Jeanne Loring of the Scripps Research Institute in La Jolla, California kindly sat down with me at the ISSCR annual meeting for a broad discussion of her history, views on the field and developments in the science. I found Jeanne a refreshing character, as I did a number of others I was fortunate to meet in Sweden. Her style I can only best describe as natural. It must be the Southern California air or something but there is a definite quality of relaxed …Read More

2 min read

For years I’ve been writing about fat stem cell clinics that sell non-FDA approved stem cell “treatments” to vulnerable patients right here in America. These clinics have been sprouting up like mushrooms across the US and their numbers may be above 200 today overall. As a result perhaps it was inevitable that one would arrive in a locale near me. Tomorrow, July 11, reportedly the Irvine Stem Cell Treatment Center will open a Sacramento, CA branch. The doctor there will apparently be Thomas A. Gionis (picture …Read More

5 min read

I invited Nobel Laureate Shinya Yamanaka to do an interview on the future of clinical translation of induced pluripotent stem cells (iPSC). He provides some intriguing new insights into the iPSC field and the broader stem cell arena. PK: The Takahashi Team’s active Clinical Study using iPSCs to make RPEs to treat Macular Degeneration has generated a great deal of excitement. Can you please share your perspectives on the importance of this work and the team involved?  SY: This is the first study to apply …Read More

3 min read

They say a little knowledge is a dangerous thing and more specifically I say that a little stem cell training for MDs, such as from A4M, can potentially be a dangerous problem too. I’ve been very concerned about self-proclaimed “stem cell training courses” for MDs. These kinds of courses have claimed that over as short as a weekend (perhaps with golf) they fully prepare physicians to do stem cell interventions on patients. Such stem cell-related procedures can yield big profits for physicians, but what about the …Read More

2 min read

Is a treatment based on stem cells for Parkinson’s Disease on the horizon? A Japanese team of researchers led by Dr. Jun Takahashi, professor at Kyoto University is reportedly aiming to start on human studies of an induced pluripotent stem (iPS) cell-based treatment for Parkinson’s Disease (PD) as early as fiscal year (FY) 2014. In Japan the FY runs from April 1-March 31 so FY2014 would begin in about 10 months. That is still remarkably fast and encouraging in the battle against PD. It …Read More